Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797530 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2368739 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2368536 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6376744 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2369269 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL231110 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8564326 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4134083 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27829038 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2368760 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759614-B | Oxazolopyridine quaternary ammonium salt compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-01-24 | — | — | CN | disclosed |
| CN-107759614-A | One class oxazole and quaternized pyridinium salt compound, preparation method and the usage | 中国科学院上海药物研究所 | 2018-03-06 | — | — | CN | disclosed |