Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL28467381 | 1.00 | GSR (0.57) | GSRPOLBKMT2ATDP1DPP8 | |
| Lysine SCHEMBL27943622 | 0.88 | GSR (0.47) | GSRPOLBKMT2ATDP1DPP8 | |
| Lysine SCHEMBL28145765 | 0.84 | GSR (0.56) | GSRPOLBKMT2ATDP1DPP8 | |
| Lysine SCHEMBL29067260 | 0.84 | GSR (0.56) | GSRPOLBKMT2ATDP1DPP8 | |
| Lysine SCHEMBL12479352 | 0.81 | GSR (0.54) | GSRPOLBKMT2ATDP1DPP8 | |
| Dipyridyl SCHEMBL28982601 | 0.81 | SLC1A5 (0.45) | POLBKMT2ATDP1SLC1A5NOS1 | |
| Benzil SCHEMBL7321827 | 0.80 | GSR (0.67) | GSRPOLBKMT2ATDP1DPP8 | |
| Benzophenone SCHEMBL6349309 | 0.80 | GSR (0.67) | GSRPOLBKMT2ATDP1DPP8 | |
| Lysine SCHEMBL1066666 | 0.80 | GSR (0.71) | GSRPOLBKMT2ATDP1DPP8 | |
| Lysine SCHEMBL1066668 | 0.80 | GSR (0.71) | GSRPOLBKMT2ATDP1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759799-A | A kind of tris (bipyridine) ruthenium lysine polymers solid phase synthesis process | 中山大学 | 2018-03-06 | — | — | CN | disclosed |
| CN-107759799-A | A kind of tris (bipyridine) ruthenium lysine polymers solid phase synthesis process | 中山大学 | 2018-03-06 | — | — | CN | disclosed |