Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28202148 | 0.79 | GSK3A (0.42) | — | |
| SCHEMBL28202187 | 0.76 | F10 (0.34) | SRCALDH1A1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL28202753 | 0.75 | DYRK1A (0.40) | ALDH1A1 | |
| SCHEMBL28202183 | 0.75 | ERN1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16432662 | 0.73 | MAP4K4 (0.42) | MAPTALPLCNR1SMN1; SMN2MEN1 | |
| SCHEMBL28202146 | 0.72 | SLC22A12 (0.44) | — | |
| SCHEMBL28202190 | 0.72 | ERN1 (0.35) | — | |
| SCHEMBL19725156 | 0.69 | TDP1 (0.38) | F2RL3SRCTDP1MAPTALDH1A1 | |
| SCHEMBL28202755 | 0.69 | CYP2C19 (0.46) | TDP1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27918809 | 0.65 | ALDH1A1 (0.44) | ALDH1A1LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473568-B | 1, 7-naphthyridine derivatives | 豪夫迈·罗氏有限公司 | 2018-02-13 | — | — | CN | claimed |
| CN-105473568-B | 1, 7-naphthyridine derivatives | 豪夫迈·罗氏有限公司 | 2018-02-13 | — | — | CN | disclosed |