Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477339 | 0.81 | PREP (0.41) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL26765821 | 0.81 | PREP (0.41) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL16824591 | 0.79 | HSD17B10 (0.42) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL610128 | 0.79 | HSD17B10 (0.42) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL16824590 | 0.79 | HSD17B10 (0.42) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL30627141 | 0.78 | PREP (0.39) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL609920 | 0.78 | NR1H2 (0.41) | CHRM2CHRM1CHRM3PREPCTSK | |
| SCHEMBL4898628 | 0.77 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL4891486 | 0.77 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPUSP2 | |
| SCHEMBL4898643 | 0.77 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793242-B | Phenoxyethyl cyclic amine derivatives and their activity as EP4 receptor modulators | 伊莱利利公司 | 2018-02-16 | — | — | CN | disclosed |