Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26765821 | 1.00 | PREP (0.41) | PREPCHRM2CHRM1CHRM3TSHR | |
| SCHEMBL17409654 | 0.83 | PREP (0.43) | PREPCHRM2CHRM1CHRM3TSHR | |
| SCHEMBL28202604 | 0.81 | CHRM2 (0.42) | PREPCHRM2CHRM1CHRM3USP2 | |
| SCHEMBL610128 | 0.80 | HSD17B10 (0.42) | PREPCHRM2CHRM1CHRM3USP2 | |
| SCHEMBL16824590 | 0.80 | HSD17B10 (0.42) | PREPCHRM2CHRM1CHRM3USP2 | |
| SCHEMBL16824591 | 0.80 | HSD17B10 (0.42) | PREPCHRM2CHRM1CHRM3USP2 | |
| SCHEMBL609920 | 0.79 | NR1H2 (0.41) | PREPCHRM2CHRM1CHRM3CTSK | |
| SCHEMBL30627141 | 0.79 | PREP (0.39) | PREPCHRM2CHRM1CHRM3USP2 | |
| SCHEMBL7870376 | 0.78 | NR1H2 (0.43) | PREPCHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL31457946 | 0.78 | PREP (0.38) | PREPCHRM2CHRM1CHRM3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051298-B | 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivative and application thereof | 诺华股份有限公司 | 2023-06-27 | — | — | CN | disclosed |