Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GPR3 | P46089 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856709 | 0.81 | NR4A2 (0.39) | MAPTTSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28203655 | 0.80 | NR4A2 (0.38) | MAPTTSHRALDH1A1CYP3A4NPC1 | |
| SCHEMBL13915654 | 0.77 | KDM4E (0.62) | KDM4EGPR3PDPK1MAPTMAPK1 | |
| SCHEMBL2680789 | 0.76 | KDM4E (0.71) | KDM4EGPR3PDPK1MAPTTSHR | |
| Phenanthridine SCHEMBL28774079 | 0.76 | GPR3 (0.95) | KDM4EGPR3PDPK1MAPTTSHR | |
| SCHEMBL19264891 | 0.75 | KDM4E (0.64) | KDM4EGPR3PDPK1MAPTTSHR | |
| SCHEMBL19055103 | 0.75 | KDM4E (0.58) | KDM4EGPR3PDPK1MAPTCYP1A2 | |
| SCHEMBL598202 | 0.74 | AKR1B1 (0.54) | KIF11MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL4766216 | 0.74 | KDM4E (0.62) | KDM4EGPR3MAPTCASP1CASP7 | |
| SCHEMBL22333732 | 0.74 | KDM4E (0.62) | KDM4EGPR3PDPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778239-A | A kind of synthetic method of phenanthridines and its derivative | 浙江工业大学 | 2018-03-09 | — | — | CN | disclosed |