Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205009 | 1.00 | AR (0.40) | ARGRM2DRD2DRD4DRD3 | |
| SCHEMBL27996855 | 0.81 | GRM2 (0.37) | GRM2 | |
| SCHEMBL807866 | 0.80 | AR (0.45) | AR | |
| SCHEMBL10279688 | 0.78 | LCAT (0.38) | AR | |
| Methylamine SCHEMBL28205497 | 0.77 | GRM2 (0.37) | ARGRM2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL795061 | 0.75 | AR (0.38) | ARGRM2 | |
| SCHEMBL27996609 | 0.75 | GRM2 (0.34) | GRM2 | |
| SCHEMBL27996612 | 0.75 | CYP3A4 (0.43) | CYP3A4KDM4EALDH1A1 | |
| SCHEMBL10279145 | 0.74 | AR (0.53) | AR | |
| Ammonia Solution, Strong SCHEMBL27989414 | 0.74 | ADRB1 (0.35) | GRM2METAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835803-A | Insecticidal aryl-pyrrolidine alkane, its preparation method and its it is used to prevent and treat the purposes of animal pest as reagent | 拜耳作物科学股份公司 | 2018-03-23 | — | — | CN | disclosed |