Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12802229 | 0.84 | SMN1; SMN2 (0.53) | ACHEPARP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16396188 | 0.84 | PBRM1 (0.59) | PBRM1MEN1KMT2AGAARAB9A | |
| Aniline SCHEMBL11007120 | 0.82 | ACHE (0.60) | PBRM1ACHESMN1; SMN2MEN1KMT2A | |
| SCHEMBL16070950 | 0.82 | ACHE (0.58) | PBRM1ACHESMN1; SMN2MEN1KMT2A | |
| Benzene SCHEMBL28200427 | 0.82 | ACHE (0.67) | ACHEMEN1KMT2AGAALMNA | |
| Aniline SCHEMBL28205031 | 0.80 | TSHR (0.58) | PBRM1PARP1MEN1KMT2ARAB9A | |
| SCHEMBL29350699 | 0.79 | — | — | |
| SCHEMBL11789 | 0.79 | — | — | |
| SCHEMBL11735289 | 0.79 | ACHE (0.71) | ACHEPARP1SMN1; SMN2MEN1KMT2A | |
| Phenol SCHEMBL11775602 | 0.79 | TDP1 (0.58) | PBRM1ACHESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739347-A | 3 methylaniline diphenyl ethylene derivatives and its production and use | 贺州学院 | 2018-02-27 | — | — | CN | disclosed |