Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2176719 | 0.73 | MEN1 (0.36) | DAOCREBBPALDH1A1MEN1KMT2A | |
| SCHEMBL18885231 | 0.71 | IDO1 (0.52) | CREBBPALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL31564905 | 0.71 | IDO1 (0.52) | CREBBPALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL28367031 | 0.64 | CREBBP (0.45) | DAOCREBBPCA12CA1CA2 | |
| SCHEMBL2587087 | 0.62 | BCHE (0.42) | DAOCREBBPCA12CA1CA2 | |
| SCHEMBL29636443 | 0.62 | BCHE (0.42) | DAOCREBBPCA12CA1CA2 | |
| Iodide SCHEMBL13386176 | 0.61 | BCHE (0.41) | DAOCREBBPCA12CA1CA2 | |
| SCHEMBL3088689 | 0.57 | DAO (1.00) | DAOALDH1A1BCHEGAAMAPT | |
| SCHEMBL8471857 | 0.57 | ALDH1A1 (0.34) | DAOCREBBPCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL11306271 | 0.57 | ALDH1A1 (0.34) | DAOCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835814-A | Azabenzimidazoles and their use as ampa receptor modulators | 詹森药业有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-107835814-A | Azabenzimidazoles and their use as ampa receptor modulators | 詹森药业有限公司 | 2018-03-23 | — | — | CN | disclosed |