Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205632 | 0.86 | ACACB (0.47) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL566349 | 0.82 | IMPDH2 (0.47) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL1063027 | 0.79 | IMPDH2 (0.51) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL30906888 | 0.76 | IMPDH2 (0.56) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL27893006 | 0.76 | IMPDH2 (0.56) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL17761613 | 0.76 | CA12 (0.51) | MAPT | |
| SCHEMBL1080464 | 0.75 | GFER (0.69) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL3486361 | 0.74 | GRM5 (0.49) | — | |
| SCHEMBL28319149 | 0.74 | IMPDH2 (0.46) | IMPDH2IMPDH1GFERAPPGRIN1 | |
| SCHEMBL1022178 | 0.73 | IMPDH2 (0.53) | IMPDH2IMPDH1GFERAPPGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107848964-A | EBNA1 inhibitors and methods of using the same | 威斯塔解剖学和生物学研究所 | 2018-03-27 | — | — | CN | claimed |
| CN-107848964-A | EBNA1 inhibitors and methods of using the same | 威斯塔解剖学和生物学研究所 | 2018-03-27 | — | — | CN | disclosed |