Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750061 | 0.77 | KDM4E (0.46) | MEN1CYP2C9KMT2ATRIM24TRIM33 | |
| SCHEMBL15635348 | 0.75 | MEN1 (0.32) | MEN1CYP2C9KMT2ATRIM24TRIM33 | |
| SCHEMBL63452 | 0.75 | EPHX1 (0.39) | MEN1CYP2C9KMT2ATRIM24TRIM33 | |
| SCHEMBL311665 | 0.74 | — | — | |
| SCHEMBL18434036 | 0.73 | KDM4E (0.33) | MEN1CYP2C9KMT2AKDM4ELMNA | |
| SCHEMBL2223857 | 0.72 | — | — | |
| SCHEMBL4602727 | 0.72 | — | — | |
| SCHEMBL1700568 | 0.71 | MEN1 (0.30) | MEN1CYP2C9KMT2A | |
| Formaldehyde SCHEMBL27736026 | 0.70 | MEN1 (0.36) | MEN1CYP2C9KMT2ATRIM24TRIM33 | |
| SCHEMBL1666431 | 0.70 | CYP19A1 (0.34) | MEN1CYP2C9KMT2ATRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743488-A | 2-oxo-1, 3, 8-triazaspiro [4.5] decan-3-yl ] carboxylic acid derivatives | 伊莱利利公司 | 2018-02-27 | — | — | CN | disclosed |