Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473163 | 0.81 | HSD17B10 (0.46) | HTTKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL18393285 | 0.80 | GALK1 (0.51) | GALK1GAAKDM4EALDH1A1HPGD | |
| SCHEMBL14268226 | 0.78 | ALDH1A1 (0.41) | GAAKDM4EALDH1A1HPGDTPMT | |
| SCHEMBL24516637 | 0.78 | GALK1 (0.50) | GALK1HTTGAAKDM4EALDH1A1 | |
| SCHEMBL12304018 | 0.77 | MEN1 (0.50) | HTTGAAKDM4EALDH1A1HPGD | |
| SCHEMBL4870888 | 0.77 | GALK1 (0.49) | GALK1HTTGAAKDM4EALDH1A1 | |
| SCHEMBL12419331 | 0.77 | GALK1 (0.59) | GALK1HTTGAAKDM4EALDH1A1 | |
| SCHEMBL4831667 | 0.77 | GALK1 (0.49) | GALK1HTTGAAKDM4EALDH1A1 | |
| SCHEMBL1164773 | 0.77 | ABL1 (0.47) | HTTGAAKDM4EALDH1A1HPGD | |
| SCHEMBL12419329 | 0.75 | GALK1 (0.51) | GALK1HTTGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743488-A | 2-oxo-1, 3, 8-triazaspiro [4.5] decan-3-yl ] carboxylic acid derivatives | 伊莱利利公司 | 2018-02-27 | — | — | CN | disclosed |