SCHEMBL28205348

SCHEMBL28205348

Cc1ccccc1Cc1ccccc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
HTT P42858 1/20 0.58
CYP2C9 P11712 2/20 0.54
HIF1A Q16665 1/20 0.54
FOLH1 Q04609 1/20 0.52
ALDH1A1 P00352 5/20 0.50
HPGD P15428 4/20 0.50
KDM4E B2RXH2 2/20 0.50
MYC P01106 1/20 0.50
HSD17B10 Q99714 1/20 0.50
SLC16A3 O15427 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
ALOX15 P16050 1/20 0.48
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 1/20 0.47
CTBP2 P56545 1/20 0.46
POLB P06746 1/20 0.46
AKR1C3 P42330 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69352 0.88 TSHR (0.68) TSHRHTTCYP2C9HIF1AFOLH1
SCHEMBL2600784 0.87 TSHR (0.56) TSHRHTTCYP2C9HIF1AFOLH1
SCHEMBL7201768 0.86 HTT (0.53) TSHRHTTCYP2C9HIF1AFOLH1
SCHEMBL1396288 0.86 HPGD (0.62) TSHRHTTCYP2C9ALDH1A1HPGD
SCHEMBL17938486 0.86 TSHR (0.66) TSHRHTTCYP2C9HIF1AFOLH1
SCHEMBL9644380 0.85 FOLH1 (0.61) TSHRHTTCYP2C9FOLH1ALDH1A1
SCHEMBL16316852 0.84 TSHR (0.61) TSHRHTTCYP2C9HIF1AFOLH1
SCHEMBL7825788 0.84 CYP2C9 (0.51) TSHRHTTCYP2C9HIF1AFOLH1
SCHEMBL8767646 0.83 HTT (0.47) TSHRHTTALDH1A1HPGDKDM4E
SCHEMBL15959651 0.82 TSHR (0.58) TSHRHTTCYP2C9HIF1AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107699917-B A kind of method of electrochemistry formated lactone 南阳师范学院 2019-02-15 CN disclosed
CN-107699917-A A kind of method of electrochemistry formated lactone 南阳师范学院 2018-02-16 CN disclosed