SCHEMBL69352

SCHEMBL69352

O=C(O)c1ccccc1Cc1ccccc1C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.68
FOLH1 Q04609 1/20 0.63
ALDH1A1 P00352 5/20 0.62
ALOX15 P16050 1/20 0.62
HIF1A Q16665 2/20 0.59
CYP2C9 P11712 1/20 0.59
AKR1C3 P42330 1/20 0.54
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 2/20 0.53
HMGB1 P09429 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CA12 O43570 1/20 0.52
HPGD P15428 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17938486 0.98 TSHR (0.66) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL4731949 0.89 HSPA5 (0.64) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL9396653 0.89 TSHR (0.58) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL15959651 0.89 TSHR (0.58) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL23003 0.89 TSHR (0.79) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL5455142 0.88 ALDH1A1 (0.61) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL8696228 0.88 TSHR (0.56) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL5808173 0.88 TSHR (0.56) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL28205348 0.88 TSHR (0.61) TSHRFOLH1ALDH1A1ALOX15HIF1A
SCHEMBL10483666 0.88 TSHR (0.56) TSHRFOLH1ALDH1A1ALOX15HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115806658-B Polyester and preparation method and application thereof 珠海万通化工有限公司 2023-11-03 CN claimed
CN-116003447-A Hg used in aqueous solution 2+ Fluorescent probe for ion detection 沈阳化工大学 2023-04-25 CN claimed
CN-115806658-A Polyester and preparation method and application thereof 珠海万通化工有限公司 2023-03-17 CN claimed
EP-2545093-A2 POLYURETHANE POLYMERS COMPRISING COPOLYESTER POLYOLS HAVING REPEAT UNITS DERIVED FROM BIOBASED -HYDROXYFATTY ACIDS Synthezyme LLC (US) 2013-01-16 EP claimed
WO-2011112923-A2 POLYURETHANE POLYMERS COMPRISING COPOLYESTER POLYOLS HAVING REPEAT UNITS DERIVED FROM BIOBASED ω-HYDROXYFATTY ACIDS SYNTHEZYME LLC (US) 2011-09-15 WO claimed
EP-0000097-B1 POLYARYLENE ESTERS MOULDING COMPOSITIONS, PROCESS FOR THEIR PREPARATION AND SHAPED ARTICLES THEREFROM MONSANTO COMPANY (US) 1981-02-11 EP claimed
US-4199493-A REINFORCING AGENT AND THERMOPLASTIC VINYL ADDITION POLYMER MONSANTO COMPANY (US) 1980-04-22 US claimed
EP-0000097-A1 Polyarylene esters moulding compositions, process for their preparation and shaped articles therefrom MONSANTO COMPANY (US) 1978-12-20 EP claimed
US-4127557-A PHENOL-TETRACHLOROETHANE SOLVENT MONSANTO COMPANY (US) 1978-11-28 US claimed
US-4028476-A LIGHTWEIGHT SHIELDS PHILLIPS PETROLEUM COMPANY (US) 1977-06-07 US claimed
US-3956228-A Polyester resin composition for powder coatings prepared from endomethylenetetrahydrophthalic acid ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-05-11 US claimed
CN-114957630-B Semi-aromatic polyester and preparation method and application thereof 珠海金发生物材料有限公司 2025-03-25 CN disclosed
CN-116023636-B Semi-aromatic polyester and preparation method and application thereof 江苏金发科技新材料有限公司 2025-03-25 CN disclosed
CN-114957628-B Polyester and preparation method and application thereof 珠海金发生物材料有限公司 2025-03-11 CN disclosed
US-12091595-B2 Curable organopolysiloxane release agent composition for thermal paper, thermal paper, and thermal recording label sheet DOW TORAY CO., LTD. (JP) 2024-09-17 US disclosed
EP-0000097-A1 Polyarylene esters moulding compositions, process for their preparation and shaped articles therefrom MONSANTO COMPANY (US) 1978-12-20 EP disclosed
US-4127557-A PHENOL-TETRACHLOROETHANE SOLVENT MONSANTO COMPANY (US) 1978-11-28 US disclosed
US-4065442-A Pyrolysis compositions from silver salts of polycarboxylic acids STANDARD OIL COMPANY (US) 1977-12-27 US disclosed
US-4028476-A LIGHTWEIGHT SHIELDS PHILLIPS PETROLEUM COMPANY (US) 1977-06-07 US disclosed
US-3839299-A AMORPHOUS POLYAMIDE FROM BIS(4-AMINOCYCLOHEXYL)METHANE, BIS(CARBOXYPHENYL)METHANE AND ALKYLENE DICARBOXYLIC ACID PHILLIPS PETROLEUM CO 1974-10-01 US disclosed