Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348292 | 0.89 | ALDH1A1 (0.53) | BRD4ALDH1A1TDP1FAAHKDM5A | |
| SCHEMBL24966152 | 0.89 | ALDH1A1 (0.53) | BRD4ALDH1A1TDP1FAAHKDM5A | |
| SCHEMBL23234281 | 0.87 | BRD4 (0.46) | BRD4ALDH1A1TDP1FAAHMAPK1 | |
| SCHEMBL24966148 | 0.87 | BRD4 (0.46) | BRD4ALDH1A1TDP1FAAHMAPK1 | |
| SCHEMBL24966182 | 0.86 | BRD4 (0.45) | BRD4ALDH1A1TDP1FAAHMAPK1 | |
| SCHEMBL24966867 | 0.83 | BRD4 (0.46) | BRD4ALDH1A1TDP1FAAHMAPK1 | |
| SCHEMBL24966866 | 0.83 | BRD4 (0.43) | BRD4ALDH1A1TDP1FAAHMAPK1 | |
| SCHEMBL24966063 | 0.82 | BRD4 (0.42) | BRD4ALDH1A1TDP1FAAHMAPK1 | |
| SCHEMBL2307447 | 0.81 | NR3C2 (0.48) | ALDH1A1 | |
| SCHEMBL24966075 | 0.81 | BRD4 (0.41) | BRD4ALDH1A1TDP1FAAHKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690281-A | Cystic fibrosis transmembrane transduction modulator modulators | 弗特克斯药品有限公司 | 2018-02-13 | — | — | CN | disclosed |