Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31690942 | 0.77 | CYP11B1 (0.38) | CYP1A2RECQLKMOELANERAB9A | |
| SCHEMBL953069 | 0.75 | CYP1A2 (0.44) | CYP1A2RECQLKMOELANERAB9A | |
| SCHEMBL31404840 | 0.75 | KDM4E (0.45) | CYP1A2MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL30419498 | 0.73 | CYP1A2 (0.51) | CYP1A2RECQLKMOELANERAB9A | |
| SCHEMBL29627707 | 0.73 | CYP1A2 (0.43) | CYP1A2RECQLKMOELANERAB9A | |
| SCHEMBL5748095 | 0.73 | CYP1A2 (0.51) | CYP1A2RECQLKMOELANERAB9A | |
| SCHEMBL102303 | 0.69 | CYP1A2 (0.63) | CYP1A2RECQLKMORAB9AMEN1 | |
| SCHEMBL6577584 | 0.69 | CA12 (0.49) | KMT2ASMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10428606 | 0.67 | RECQL (0.44) | CYP1A2RECQLKMOELANERAB9A | |
| SCHEMBL6905058 | 0.67 | RECQL (0.44) | CYP1A2RECQLKMOELANERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981766-A1 | INDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Eisai R&D Management Co., Ltd. (JP) | 2022-04-13 | — | — | EP | disclosed |
| CN-107847498-A | tetra-substituted olefin compound and use thereof | 卫材R&D管理有限公司 | 2018-03-27 | — | — | CN | disclosed |