Styrene

Styrene

SCHEMBL2820693

C=Cc1ccccc1.C=Cc1ccccc1C=C.C=Cc1ccccn1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 1/20 0.50
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ATM Q13315 1/20 0.47
MAOA P21397 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NR4A1 P22736 1/20 0.38
USP2 O75604 1/20 0.38
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
IP6K1 Q92551 1/20 0.35
GRM4 Q14833 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL607743 0.93 ALDH1A1 (0.58) ALDH1A1TSHRNPC1RAB9AMEN1
SCHEMBL753718 0.91 NPC1 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A
Styrene SCHEMBL27506927 0.89 ALDH1A1 (0.54) ALDH1A1TSHRNPC1RAB9AMEN1
Styrene SCHEMBL27860637 0.89 ALDH1A1 (0.54) ALDH1A1TSHRNPC1RAB9AMEN1
Styrene SCHEMBL77127 0.89 ALDH1A1 (0.54) ALDH1A1TSHRNPC1RAB9AMEN1
Styrene SCHEMBL27564658 0.86 ALDH1A1 (0.50) ALDH1A1TSHRNPC1RAB9AMEN1
Benzene SCHEMBL27612258 0.84 MEN1 (0.64) ALDH1A1TSHRNPC1RAB9AMEN1
Styrene SCHEMBL28823018 0.84 TSHR (0.48) ALDH1A1TSHRNPC1RAB9AMEN1
Styrene SCHEMBL28871868 0.84 NPC1 (0.49) ALDH1A1TSHRNPC1RAB9AMEN1
Styrene SCHEMBL6473938 0.83 ALDH1A1 (0.47) ALDH1A1TSHRNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107923128-B Thin sheet paper 花王株式会社 2019-02-15 CN claimed
CN-107923128-A Thin sheet paper 花王株式会社 2018-04-17 CN claimed
US-4147730-A PLATINUM HALIDE AND GROUP 4 METAL HALIDE CATALYSTS ON POLYMERIC OR TEXACO INC. (US) 1979-04-03 US claimed
JP-63077504-A None JP disclosed
CN-115362182-A Hydrophilic oil-repellent polymers 住友化学株式会社 2022-11-18 CN disclosed
CN-110913818-B Absorbent article 花王株式会社 2022-05-17 CN disclosed
US-11203674-B2 Transparent film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-21 US disclosed
CN-109071817-B Composition comprising a metal oxide and a metal oxide 住友化学株式会社 2021-11-09 CN disclosed
CN-113631636-A Composition and film 住友化学株式会社 2021-11-09 CN disclosed
US-11136473-B2 Fluorine-containing coating film and water- and oil-repellent coating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-10-05 US disclosed
CN-109071819-B Composition comprising a metal oxide and a metal oxide 住友化学株式会社 2021-09-21 CN disclosed
CN-101802189-B Beta-glucuronidase inhibitor KAO CORP 2013-03-27 CN disclosed
US-20100247475-A1 BETA-GLUCURONIDASE INHIBITOR KAO CORPORATION (JP) 2010-09-30 US disclosed
EP-2192178-A1 B-GLUCURONIDASE INHIBITOR Kao Corporation (JP) 2010-06-02 EP disclosed
JP-S6377504-A METHOD FOR DESALTING ORGANIC MATTER TOKUYAMA SODA CO LTD 1988-04-07 JP disclosed
US-4147730-A PLATINUM HALIDE AND GROUP 4 METAL HALIDE CATALYSTS ON POLYMERIC OR TEXACO INC. (US) 1979-04-03 US disclosed
US-4140815-A ELECTRODIALYSIS ALLIED CHEMICAL CORPORATION (US) 1979-02-20 US disclosed
US-4083768-A PRESWOLLEN, CROSSLINKED POLYOLEFIN MATRIX ALLIED CHEMICAL CORPORATION (US) 1978-04-11 US disclosed
US-4057481-A CROSSLINKING AN OLEFIN POLYMER FILM, CLEANING, FUNCTIONALIZING WITH IONIC GROUPS ALLIED CHEMICAL CORPORATION (US) 1977-11-08 US disclosed
US-4024043-A ION SELECTIVITY ALLIED CHEMICAL CORPORATION (US) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247475-A1 BETA-GLUCURONIDASE INHIBITOR GUSB, GAA, GANAB ALDH1A1 28/4885TSHR 3938/4885NPC1 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.