Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.82 |
| ▸ | TSHR | P16473 | 4/20 | 0.82 |
| ▸ | LMNA | P02545 | 3/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.72 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.72 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983655 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28827218 | 0.97 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28829154 | 0.97 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28217941 | 0.97 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL9697816 | 0.97 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11130022 | 0.97 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27783236 | 0.94 | PRSS1 (0.73) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL28000203 | 0.94 | PRSS1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11327327 | 0.92 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL1604877 | 0.92 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025086-A | Antibody-active agent conjugates (ADC) of KSP inhibitors and anti-B7H 3 antibodies | 拜耳制药股份公司 | 2018-05-11 | — | — | CN | disclosed |