SCHEMBL28207458

SCHEMBL28207458

O=C(OCc1ccccc1)C(Cc1ccccc1)c1ccccc1.O=C(OCc1ccccc1)C(Cc1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 5/20 0.63
EPHX1 P07099 1/20 0.61
ALDH1A1 P00352 4/20 0.52
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
CTRB1 P17538 2/20 0.49
UBE2N P61088 1/20 0.49
LTA4H P09960 1/20 0.48
LAP3 P28838 1/20 0.48
LMNA P02545 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14691416 1.00 CHRM1 (0.63) CHRM1EPHX1ALDH1A1MAPK1L3MBTL1
SCHEMBL28394711 0.86 ATM (0.59) CHRM1EPHX1TDP1ESR1ESR2
SCHEMBL21634088 0.86 ALDH1A1 (0.52) CHRM1EPHX1ALDH1A1MAPK1L3MBTL1
SCHEMBL27494792 0.86 ALDH1A1 (0.52) CHRM1EPHX1ALDH1A1MAPK1L3MBTL1
SCHEMBL7298763 0.84 ALDH1A1 (0.50) CHRM1EPHX1ALDH1A1MAPK1L3MBTL1
SCHEMBL6220408 0.84 ALDH1A1 (0.50) CHRM1EPHX1ALDH1A1MAPK1L3MBTL1
SCHEMBL28002113 0.84 ALDH1A1 (0.50) CHRM1EPHX1ALDH1A1MAPK1L3MBTL1
SCHEMBL27410877 0.84 ALDH1A1 (0.55) CHRM1ALDH1A1MAPK1L3MBTL1SLC6A2
SCHEMBL15553196 0.84 CHRM1 (0.66) CHRM1EPHX1ALDH1A1ESR1ESR2
SCHEMBL10691182 0.82 EPHX1 (0.61) CHRM1EPHX1ESR1ESR2UBE2N

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107880085-A One kind utilizes [Rmim] [OSO2OR] Lewis acid ions liquid system synthesis rhodioside method 枣庄学院 2018-04-06 CN disclosed