Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | FDPS | P14324 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medronic Acid SCHEMBL5489208 | 0.81 | ANPEP (0.44) | METAP1LAP3S1PR2S1PR1S1PR3 | |
| Medronic Acid SCHEMBL14696178 | 0.79 | ANPEP (0.43) | S1PR2S1PR1S1PR3S1PR4ANPEP | |
| SCHEMBL361463 | 0.79 | — | — | |
| SCHEMBL249459 | 0.79 | — | — | |
| SCHEMBL4327895 | 0.79 | — | — | |
| Medronic Acid SCHEMBL6865555 | 0.78 | METAP1 (0.47) | METAP1FDPSLAP3ANPEPERAP2 | |
| Medronic Acid SCHEMBL9684269 | 0.77 | METAP1 (0.44) | METAP1FDPSLAP3S1PR2S1PR1 | |
| Hydrochloric Acid SCHEMBL4281442 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL6376822 | 0.77 | — | — | |
| SCHEMBL15710900 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802891-B2 | Process for the manufacture of alkylamino alkylene phosphonic acids | ITALMATCH CHEMICALS SPA (IT) | 2014-08-12 | — | — | US | disclosed |
| EP-2125842-B1 | PROCESS FOR THE MANUFACTURE OF ALKYLAMINO ALKYLENE PHOSPHONIC ACIDS | ITALMATCH CHEMICALS SPA (IT) | 2014-05-21 | — | — | EP | disclosed |
| US-20100174110-A1 | PROCESS FOR THE MANUFACTURE OF ALKYLAMINO ALKYLENE PHOSPHONIC ACIDS | THERMPHOS TRADING GMBH (CH) | 2010-07-08 | — | — | US | disclosed |
| EP-1932848-A1 | Process for the manufacture of alkylamino alkylene phosphonic acids | Thermphos Trading GmbH (CH) | 2008-06-18 | — | — | EP | disclosed |