Medronic Acid

Medronic Acid

SCHEMBL6865555

CCCC(C)CN.N.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 2/20 0.47
FDPS P14324 4/20 0.45
LAP3 P28838 3/20 0.40
KDM4E B2RXH2 1/20 0.40
MMP2 P08253 1/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GABBR2 O75899 2/20 0.39
GABBR1 Q9UBS5 2/20 0.39
TSHR P16473 1/20 0.38
ANPEP P15144 1/20 0.37
ERAP2 Q6P179 1/20 0.37
OTC P00480 1/20 0.37
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Medronic Acid SCHEMBL10604300 0.80 LMNA (0.41) FDPSLAP3KDM4EMMP2THRB
Medronic Acid SCHEMBL2820764 0.78 METAP1 (0.50) METAP1FDPSLAP3KDM4EMMP2
SCHEMBL104640 0.78
SCHEMBL18085391 0.78
SCHEMBL17928911 0.78
Hydrochloric Acid SCHEMBL7779007 0.75
Medronic Acid SCHEMBL9167217 0.75 KDM4E (0.62) METAP1FDPSLAP3KDM4EMMP2
SCHEMBL6412081 0.74 ALDH1A1 (0.50) METAP1LAP3GABBR2GABBR1ANPEP
Medronic Acid SCHEMBL243320 0.73 ALDH1A1 (0.53) METAP1FDPSLAP3KDM4EMMP2
Medronic Acid SCHEMBL10634361 0.73 ALDH1A1 (0.53) METAP1FDPSLAP3KDM4EMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6814930-B1 FOR TREATING COOLING WATER IN EVAPORATIVE WATER COOLING SYSTEMS CONSISTING ESSENTIALLY OF: ORGANOPHOSPHOROUS COMPOUNDS, TANNINS AND WATER Kurita America, Inc. 2004-11-09 US claimed
US-6468470-B1 WHITE RUST INHIBITOR FOR EVAPORATIVE WATER COOLERS COMPRISING SUCH AS 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID, TANNINS AND SODIUM MOLYBDATE; RESISTANT TO OXIDIZING MICROBIOCIDES FREMONT INDUSTRIES, INC. 2002-10-22 US claimed
US-5407597-A Organophosphorus compound, carbamate, and water soluble metal compound FREMONT INDUSTRIES, INC. (US) 1995-04-18 US claimed
US-6814930-B1 FOR TREATING COOLING WATER IN EVAPORATIVE WATER COOLING SYSTEMS CONSISTING ESSENTIALLY OF: ORGANOPHOSPHOROUS COMPOUNDS, TANNINS AND WATER Kurita America, Inc. 2004-11-09 US disclosed
US-6468470-B1 WHITE RUST INHIBITOR FOR EVAPORATIVE WATER COOLERS COMPRISING SUCH AS 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID, TANNINS AND SODIUM MOLYBDATE; RESISTANT TO OXIDIZING MICROBIOCIDES FREMONT INDUSTRIES, INC. 2002-10-22 US disclosed
US-5407597-A Organophosphorus compound, carbamate, and water soluble metal compound FREMONT INDUSTRIES, INC. (US) 1995-04-18 US disclosed