SCHEMBL28207690

SCHEMBL28207690

CC(C)(C)OC(=O)C(C)(Br)S(C)(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
CA12 O43570 5/20 0.34
CA14 Q9ULX7 5/20 0.34
CA2 P00918 2/20 0.34
CA1 P00915 3/20 0.33
CA9 Q16790 1/20 0.33
CA7 P43166 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25713873 0.73 DGAT1 (0.41) DGAT1CA12CA14CA2CA1
SCHEMBL161854 0.72 DGAT1 (0.50) DGAT1
SCHEMBL11552854 0.72 DGAT1 (0.50) DGAT1
SCHEMBL14606262 0.72 DGAT1 (0.50) DGAT1
SCHEMBL16569303 0.71 DGAT1 (0.36) DGAT1CA12CA14CA2CA1
SCHEMBL16569301 0.71 DGAT1 (0.36) DGAT1CA12CA14CA2CA1
SCHEMBL16569342 0.71 DGAT1 (0.36) DGAT1CA12CA14CA2CA1
SCHEMBL16569687 0.70 DGAT1 (0.39) DGAT1CA12CA14CA2CA1
SCHEMBL16569689 0.70 DGAT1 (0.39) DGAT1CA12CA14CA2CA1
SCHEMBL21058313 0.69 DGAT1 (0.46) DGAT1CA12CA14CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026100-A Substituted 1, 2-dihydro-3H-pyrrolo [1,2-c ] imidazol-3-one antibacterial agents 爱杜西亚药品有限公司 2018-05-11 CN disclosed