Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331295 | 0.81 | EGFR (0.45) | MEN1KMT2AALDH1A1TSHRRORC | |
| SCHEMBL28183120 | 0.79 | TSHR (0.43) | MEN1KMT2ATSHRKDM4EL3MBTL1 | |
| SCHEMBL19332261 | 0.78 | MCL1 (0.36) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL17775142 | 0.75 | TSHR (0.37) | MEN1KMT2AALDH1A1TSHRRORC | |
| SCHEMBL28064638 | 0.74 | MCL1 (0.47) | MEN1KMT2ATSHRRORCKDM4E | |
| SCHEMBL19332440 | 0.74 | USP2 (0.36) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL4351610 | 0.73 | JAK2 (0.41) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1092586 | 0.73 | KDM4E (0.67) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL30639179 | 0.73 | KDM4E (0.67) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL5799161 | 0.72 | EGFR (0.41) | KMT2AALDH1A1KDM4EL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555763-B | indole-carboxamide derivatives | 豪夫迈·罗氏有限公司 | 2018-04-17 | — | — | CN | disclosed |