Carbazole

Carbazole

SCHEMBL28208015

N#Cc1cccc2cc3ccccc3cc12.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.55
CLK1 P49759 2/20 0.55
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46
GABRG3 Q99928 1/20 0.46
GABRQ Q9UN88 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32172 0.86 CA1 (0.52) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL31050902 0.86 CA1 (0.52) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL31050903 0.86 CA1 (0.52) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL30858824 0.84 CA1 (0.50) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL16875674 0.84 CA1 (0.50) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL28488846 0.84 CA1 (0.50) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL28863050 0.84 DYRK1A (0.50) DYRK1ACLK1CDK5CDK5R1CLK2
Carbazole SCHEMBL28286043 0.80 ALDH1A1 (0.64) DYRK1ACLK1GABRPGABRDGABRA1
SCHEMBL18322219 0.80 HTT (0.53) DYRK1ACLK1ALDH1A1HSD17B10CA1
SCHEMBL818940 0.78 HTT (0.52) DYRK1ACLK1ALDH1A1HSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110058344-A Optical film 住友化学株式会社 2019-07-26 CN disclosed
CN-104345370-B Optical film 住友化学株式会社 2018-08-24 CN disclosed
CN-104345372-B Optical film 住友化学株式会社 2018-04-10 CN disclosed