Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 16/20 | 0.61 |
| ▸ | LPAR5 | Q9H1C0 | 16/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16507443 | 0.84 | HDAC1 (0.59) | HDAC1HDAC6LPAR1LPAR5PKM | |
| SCHEMBL16506463 | 0.76 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL14720201 | 0.75 | HDAC1 (0.52) | HDAC1HDAC6LPAR1LPAR5PKM | |
| SCHEMBL16506625 | 0.75 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16506976 | 0.75 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16506833 | 0.75 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16506837 | 0.75 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16507344 | 0.74 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16506601 | 0.74 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL16506872 | 0.71 | LPAR1 (1.00) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473548-B | Amide derivatives as lpa receptor antagonist | 武田药品工业株式会社 | 2018-03-23 | — | — | CN | disclosed |