Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720344 | 0.86 | OPRM1 (0.42) | — | |
| SCHEMBL14720186 | 0.86 | JAK2 (0.52) | HDAC1HDAC6PKMKMT2A | |
| SCHEMBL14720297 | 0.81 | LIMK2 (0.48) | CHRM3CHRM2KMT2A | |
| SCHEMBL13739207 | 0.78 | SMN1; SMN2 (0.46) | CHRM3CHRM2TACR3 | |
| SCHEMBL13738435 | 0.78 | SMN1; SMN2 (0.46) | CHRM3CHRM2TACR3 | |
| SCHEMBL14720668 | 0.78 | OPRD1 (0.39) | CHRM3CHRM2KMT2A | |
| SCHEMBL15668019 | 0.76 | OPRM1 (0.48) | TACR3 | |
| SCHEMBL15668020 | 0.76 | OPRM1 (0.48) | TACR3 | |
| SCHEMBL28208196 | 0.75 | HDAC1 (0.64) | HDAC1HDAC6PKMLPAR1LPAR5 | |
| SCHEMBL14720449 | 0.75 | CHRM3 (0.52) | CHRM3CHRM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |