Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31673035 | 0.83 | ESR1 (0.41) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL14920227 | 0.80 | TRPV4 (0.43) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL2693449 | 0.80 | AR (0.47) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL2148663 | 0.78 | TSHR (0.43) | ARESR1ESR2TSHRUPP1 | |
| SCHEMBL6364089 | 0.78 | TRPV4 (0.42) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL16122042 | 0.77 | TRPV4 (0.41) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL24495511 | 0.75 | AR (0.45) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL31156144 | 0.75 | AR (0.40) | ARESR1ESR2TRPV4CYP11B1 | |
| SCHEMBL27709086 | 0.75 | AR (0.40) | ARTSHRUPP1 | |
| SCHEMBL3426156 | 0.75 | AR (0.41) | ARTRPV4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922396-A | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 建新公司 | 2018-04-17 | — | — | CN | disclosed |