⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406287 | 0.98 | SIGMAR1 (0.33) | — | |
| SCHEMBL8406290 | 0.82 | — | — | |
| SCHEMBL8406247 | 0.81 | SIGMAR1 (0.43) | — | |
| SCHEMBL8406328 | 0.79 | F2 (0.31) | — | |
| SCHEMBL6908034 | 0.75 | — | — | |
| SCHEMBL15848998 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL8406296 | 0.74 | — | — | |
| SCHEMBL8406283 | 0.73 | PIK3CD (0.31) | — | |
| SCHEMBL21660053 | 0.73 | — | — | |
| SCHEMBL8406280 | 0.70 | F2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922396-A | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 建新公司 | 2018-04-17 | — | — | CN | disclosed |