⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62851 | 0.80 | — | — | |
| SCHEMBL62852 | 0.80 | — | — | |
| SCHEMBL3071634 | 0.80 | — | — | |
| SCHEMBL723877 | 0.80 | CYP2D6 (0.41) | — | |
| SCHEMBL164980 | 0.80 | — | — | |
| SCHEMBL28777357 | 0.79 | SLC7A5 (0.40) | — | |
| SCHEMBL8741964 | 0.78 | CYP2D6 (0.40) | — | |
| SCHEMBL161194 | 0.78 | — | — | |
| SCHEMBL21641518 | 0.78 | — | — | |
| SCHEMBL594190 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103748142-B | Reversibly crosslinked micelle systems | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-04-27 | — | — | CN | claimed |
| CN-105188717-A | Porphyrin modified telodendrimers | UNIV CALIFORNIA | 2015-12-23 | — | — | CN | claimed |
| CN-104105508-A | Drug delivery enhanced terminal dendrimers | UNIV CALIFORNIA | 2014-10-15 | — | — | CN | claimed |
| CN-103748142-A | Reversibly crosslinked micelle systems | UNIV CALIFORNIA | 2014-04-23 | — | — | CN | claimed |
| CN-102159189-B | Nanocarriers for drug delivery | UNIV CALIFORNIA | 2013-06-12 | — | — | CN | claimed |
| CN-102159189-A | Nanocarriers for drug delivery | UNIV CALIFORNIA | 2011-08-17 | — | — | CN | claimed |
| EP-0606532-B1 | Silicone polyelectrolyte aqueous coating solution | MINNESOTA MINING & MFG (US) | 2001-05-30 | — | — | EP | claimed |
| US-5543171-A | A DIMETHYLSILOXANE CONTAINING POLYELECTROLYTE INCORPORATING OXYGEN, NITROGEN OR SULFUR CONTAINING POLAR GROUPS AND ANIONIC GROUPS | RX TECHNOLOGY CORP. | 1996-08-06 | — | — | US | claimed |
| EP-0606532-A1 | Silicone polyelectrolyte aqueous coating solution | Shores, Andrew A. (US) | 1994-07-20 | — | — | EP | claimed |
| CN-115551917-B | Sequential targeting of cross-linked nanotherapeutics for the treatment of brain tumors | 加利福尼亚大学董事会 | 2025-06-13 | — | — | CN | disclosed |
| CN-111491551-B | Compositions and devices for removing endotoxins and cytokines from fluids | 纽约州立大学研究基金会 | 2023-11-17 | — | — | CN | disclosed |
| WO-2018195078-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-10-25 | — | — | WO | disclosed |
| EP-3263586-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2018-01-03 | — | — | EP | disclosed |
| EP-3078672-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2016-10-12 | — | — | EP | disclosed |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-08-27 | — | — | US | disclosed |
| WO-2009098357-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2009-08-13 | — | — | WO | disclosed |
| EP-2057185-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2009-05-13 | — | — | EP | disclosed |
| US-20080287345-A1 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2008-11-20 | — | — | US | disclosed |
| WO-2008017734-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |