Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.60 |
| ▸ | PNMT | P11086 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969138 | 0.95 | CYP19A1 (0.56) | LOXL2PNMTENPP2PRMT6NOS1 | |
| SCHEMBL920626 | 0.93 | LOXL2 (0.67) | LOXL2PNMTENPP2PRMT6NOS1 | |
| SCHEMBL36008 | 0.91 | LOXL2 (0.71) | LOXL2PNMTENPP2PRMT6NOS1 | |
| SCHEMBL10422276 | 0.91 | LOXL2 (0.71) | LOXL2PNMTENPP2PRMT6NOS1 | |
| Hydrochloric Acid SCHEMBL1237382 | 0.91 | LOXL2 (0.64) | LOXL2PNMTENPP2PRMT6NOS1 | |
| SCHEMBL2642524 | 0.90 | TAAR1 (0.61) | LOXL2PNMTENPP2PRMT6NOS1 | |
| Hydrochloric Acid SCHEMBL6018896 | 0.88 | LOXL2 (0.67) | LOXL2PNMTENPP2PRMT6NOS1 | |
| Ammonia Solution, Strong SCHEMBL6899866 | 0.88 | LOXL2 (0.67) | LOXL2PNMTENPP2PRMT6NOS1 | |
| Hydrochloric Acid SCHEMBL8195914 | 0.88 | LOXL2 (0.67) | LOXL2PNMTENPP2PRMT6NOS1 | |
| Bromide SCHEMBL28362115 | 0.88 | LOXL2 (0.67) | LOXL2PNMTENPP2PRMT6NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827693-A | The method of graphene-supported palladium/platinum catalysis sp3C H keys coupling 1,2 diphenyl ethane derivatives of synthesis | 湖南大学 | 2018-03-23 | — | — | CN | disclosed |