⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754334 | 0.90 | TDP1 (0.31) | — | |
| SCHEMBL1670 | 0.90 | — | — | |
| SCHEMBL28182677 | 0.87 | — | — | |
| Bromide SCHEMBL28123900 | 0.87 | — | — | |
| SCHEMBL9397770 | 0.87 | — | — | |
| SCHEMBL27701016 | 0.87 | — | — | |
| SCHEMBL28082245 | 0.87 | — | — | |
| Methylene Chloride SCHEMBL28232559 | 0.85 | — | — | |
| SCHEMBL28871555 | 0.84 | — | — | |
| SCHEMBL28240029 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099682-A | Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-109912683-A | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-108811499-A | Specific conjugation of cell binding molecules | 苏州美康加生物科技有限公司 | 2018-11-13 | — | — | CN | disclosed |
| CN-108449940-A | Conjugated bridge linkers to cell binding molecules | 苏州美康加生物科技有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-108289964-A | Novel linkers and their use for specific coupling of drugs and biomolecules | 苏州美康加生物科技有限公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-108026123-A | Hydrophilic linkers for coupling | 杭州多禧生物科技有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107921144-A | Auristatin analogs and conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2018-04-17 | — | — | CN | disclosed |