SCHEMBL754334

SCHEMBL754334

CC(C)(C)O[C]=O.CC(C)(C)O[C]=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1670 1.00
SCHEMBL9397770 0.96
SCHEMBL28871555 0.93
SCHEMBL5264159 0.81
Methylamine SCHEMBL18979545 0.81
SCHEMBL8751772 0.80
SCHEMBL2185750 0.72
SCHEMBL2153342 0.72
SCHEMBL15767062 0.72
SCHEMBL5931931 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024022465-A1 HUMAN AMYLIN POLYPEPTIDE DERIVATIVE AND USE THEREOF 杭州九源基因工程有限公司 2024-02-01 WO disclosed
EP-4238979-A1 BETA-STRAND TYPE CROSSLINKED PEPTIDE Xeno-Interface Inc. (JP) 2023-09-06 EP disclosed
EP-3495349-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2023-06-28 EP disclosed
US-20230174576-A1 BETA-STRAND BRIDGE PEPTIDE KYOTO UNIVERSITY (JP) 2023-06-08 US disclosed
EP-3736265-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS Oryzon Genomics, S.A. (ES) 2020-11-11 EP disclosed
EP-2768805-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2020-03-25 EP disclosed
CN-109970720-A A kind of Aurora A protein inhibitor and preparation method thereof and medicinal usage 深圳先进技术研究院 2019-07-05 CN disclosed
US-10329256-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS, S.A. (ES) 2019-06-25 US disclosed
EP-3495349-A1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS Oryzon Genomics, S.A. (ES) 2019-06-12 EP disclosed
EP-2776394-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2018-12-26 EP disclosed
EP-0672679-B1 PHOSPHOLIPASE C INHIBITING PEPTIDE KYOWA HAKKO KOGYO KK (JP) 1998-01-28 EP disclosed
EP-0421682-B1 Novel peptides, intermediates therefor, process for preparing the same, and antiallergic agents, vasodilators and immunoregulators HITACHI CHEMICAL CO LTD (JP) 1997-03-26 EP disclosed
EP-0672679-A1 PHOSPHOLIPASE C INHIBITING PEPTIDE KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1995-09-20 EP disclosed
US-5223487-A Tri-, tetra-, penta- and hexapeptatides of Asp, Gly, Lys, Ser, Ala and salts HITACHI CHEMICAL CO., LTD. (JP) 1993-06-29 US disclosed
US-5095139-A Fungicides CIBA-GEIGY CORPORATION (US) 1992-03-10 US disclosed
EP-0421682-A1 Novel peptides, intermediates therefor, process for preparing the same, and antiallergic agents, vasodilators and immunoregulators HITACHI CHEMICAL CO., LTD. (JP) 1991-04-10 EP disclosed
US-H810-H MORPHINE AGONIST Wilkinson, Samuel (GB) 1990-08-07 US disclosed
EP-0122818-B1 LIQUID-PHASE SYNTHESIS OF HPGRF (SOMATOCRININ) AND INTERMEDIATE PEPTIDES SANOFI S.A. (FR) 1987-10-07 EP disclosed
EP-0057419-B1 NEW PEPTIDE, PROCESS FOR PREPARATION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-12-27 EP disclosed
US-4115646-A Process for preparing 7-aminocephalosporanic acid derivatives BEECHAM GROUP LIMITED (GB) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174576-A1 BETA-STRAND BRIDGE PEPTIDE IAPP, SPPL2B, VIP TDP1 2335/4885TSHR 2483/4885ALDH1A1 4642/4885
US-10329256-B2 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors KDM1B, KDM1A, KDM2A TDP1 409/4885TSHR 4274/4885ALDH1A1 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.