Acrylonitrile

Acrylonitrile

SCHEMBL28209167

C=CC#N.C=CC=CCC(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
CYP2D6 P10635 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.38
PAM P19021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633425 0.87
SCHEMBL5176784 0.87
Acrylonitrile SCHEMBL2578377 0.78 ALDH1A1 (0.45) ALDH1A1CYP2D6ALOX15TSHR
SCHEMBL27912109 0.78 ALDH1A1 (0.52) ALDH1A1CYP2D6ALOX15PAM
SCHEMBL2698550 0.78 ALDH1A1 (0.52) ALDH1A1CYP2D6ALOX15PAM
SCHEMBL17950790 0.78 ALDH1A1 (0.52) ALDH1A1CYP2D6ALOX15PAM
SCHEMBL17540715 0.78 ALDH1A1 (0.52) ALDH1A1CYP2D6ALOX15PAM
SCHEMBL2698556 0.78 ALDH1A1 (0.52) ALDH1A1CYP2D6ALOX15PAM
SCHEMBL17540714 0.78 ALDH1A1 (0.52) ALDH1A1CYP2D6ALOX15PAM
SCHEMBL28963153 0.74 ALDH1A1 (0.55) ALDH1A1CYP2D6ALOX15PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107778564-A A kind of nitrile rubber is ageing-resistant material modified and preparation method thereof 四川力智久创知识产权运营有限公司 2018-03-09 CN disclosed