SCHEMBL28209261

SCHEMBL28209261

O=[N+]([O-])c1n[nH]c(-c2n[nH]c([N+](=O)[O-])n2)n1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1172467 0.82 CYP1A2 (0.40) CYP1A2CYP2C9MAPT
SCHEMBL15776050 0.82 MAPT (0.35) MEN1LMNAMAPTKMT2A
SCHEMBL6131347 0.80 CYP1A2 (0.39) CYP1A2CYP2C9MAPT
Potassium Ion SCHEMBL6131368 0.80 CYP1A2 (0.39) CYP1A2CYP2C9MAPT
Ammonia Solution, Strong SCHEMBL9727420 0.80 CYP1A2 (0.39) CYP1A2CYP2C9MAPT
Potassium SCHEMBL6131371 0.80 CYP1A2 (0.39) CYP1A2CYP2C9MAPT
SCHEMBL11318233 0.80 CYP1A2 (0.53) CYP1A2CYP2C9MEN1LMNAMAPT
SCHEMBL18284832 0.69 LMNA (0.59) CYP1A2MEN1LMNAMAPTKMT2A
Ammonia Solution, Strong SCHEMBL9727425 0.67 CYP1A2 (0.36) CYP1A2CYP2C9
SCHEMBL6131370 0.67 CYP1A2 (0.36) CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104649984-B 1,1 ' two (together with dinitro methyl) 3,3 ' dinitros 5,5 ' join the double hydroxylamine salts of 1,2,4 triazoles 西安近代化学研究所 2018-04-20 CN disclosed