Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17560417 | 0.98 | KDM4E (0.38) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL5202006 | 0.87 | KDM4E (0.41) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL6491224 | 0.85 | KMT2A (0.39) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL16457810 | 0.85 | KDM4E (0.47) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL17560414 | 0.83 | KDM4E (0.32) | KDM4EKMT2ANOS2 | |
| SCHEMBL476505 | 0.81 | KDM4E (0.44) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL7161151 | 0.81 | SLC6A1 (0.41) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL5200159 | 0.78 | KMT2A (0.37) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL30342367 | 0.78 | KDM4E (0.31) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL4496703 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107912040-A | Pyrrolidine Amide Compounds As Histone Demethylase Inhibitors | 基因泰克公司 | 2018-04-13 | — | — | CN | disclosed |