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Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL28209384

NC(=O)CC(N)C(=O)O.NC(CO)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O.NCCCCC(N)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.41
▸ OPRM1 P35372 1/20 0.40
▸ ITGB3 P05106 1/20 0.37
▸ ITGA2B P08514 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ITGA4 P13612 6/20 0.36
▸ ERAP2 Q6P179 1/20 0.35
▸ LNPEP Q9UIQ6 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ GSR P00390 1/20 0.34
▸ PLAU P00749 2/20 0.34
▸ PLAUR Q03405 2/20 0.34
▸ ITGB1 P05556 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL17728305 0.95 SLC7A5 (0.46) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL15971883 0.95 SLC7A5 (0.46) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL17728311 0.95 SLC7A5 (0.46) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL6246872 0.94 OPRM1 (0.37) SLC7A5OPRM1THRB
Tyrosine SCHEMBL15972448 0.91 SLC7A5 (0.43) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL17728302 0.91 SLC7A5 (0.43) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL15972075 0.91 SLC7A5 (0.43) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL15264616 0.91 SLC7A5 (0.50) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL7434891 0.91 SLC7A5 (0.50) SLC7A5OPRM1ITGB3ITGA2BMAPT
Tyrosine SCHEMBL15972071 0.88 SLC7A5 (0.40) SLC7A5OPRM1ITGB3ITGA2BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107779489-B Silkworm pupa protein peptide with oxidation resistance and ACE (angiotensin converting enzyme) inhibition functions 安徽国肽生物科技有限公司 2020-05-22 — — CN claimed
CN-107779489-B Silkworm pupa protein peptide with oxidation resistance and ACE (angiotensin converting enzyme) inhibition functions 安徽国肽生物科技有限公司 2020-05-22 — — CN disclosed
CN-107779489-A A kind of pupa albumen peptide for suppressing function with anti-oxidant and ACE 安徽国肽生物科技有限公司 2018-03-09 — — CN disclosed