Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 10/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.55 |
| ▸ | PTGFR | P43088 | 3/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870078 | 0.84 | PTGER3 (0.56) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL4002939 | 0.82 | ALOX5 (0.58) | ALOX5HSD17B3 | |
| SCHEMBL157606 | 0.82 | PTGER3 (0.73) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL2979100 | 0.81 | PTGER3 (0.65) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL2979103 | 0.81 | PTGER3 (0.65) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL26046320 | 0.81 | MIF (0.60) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL10350184 | 0.81 | MIF (0.60) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL9447849 | 0.81 | MIF (0.60) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| Biphenyl SCHEMBL28775819 | 0.81 | MIF (0.53) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL28225268 | 0.78 | ALOX5 (0.56) | ALOX5HSD17B3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330630-B | Benzofuran compounds and its preparation method and application | 上海交通大学 | 2018-04-17 | — | — | CN | disclosed |