Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373769 | 0.81 | KDM4E (0.62) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL27481837 | 0.81 | KDM4E (0.62) | KMT2AKDM4EALDH1A1GLAGAA | |
| Ethoxycoumarin SCHEMBL4574788 | 0.79 | CA9 (0.63) | KMT2AKDM4EALDH1A1GLAGAA | |
| Glucuronate SCHEMBL14343105 | 0.76 | KDM4E (0.59) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL19900163 | 0.76 | KMT2A (0.87) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL1944338 | 0.75 | CA12 (0.54) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL560234 | 0.74 | ALDH1A1 (0.69) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6753312 | 0.74 | ALDH1A1 (0.69) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL3224389 | 0.74 | TYR (0.41) | KMT2AKDM4EGLAGAACA12 | |
| SCHEMBL2234966 | 0.74 | TYR (0.41) | KMT2AKDM4EGLAGAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111684058-B | Method for inducing differentiation from pluripotent stem cells into intestinal epithelial cells | 公立大学法人名古屋市立大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-113194951-A | Topical formulations of DGAT1 inhibitors and methods of use thereof | 德马万特科学股份有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-111684058-A | Method for inducing differentiation from pluripotent stem cells into intestinal epithelial cells | 公立大学法人名古屋市立大学 | 2020-09-18 | — | — | CN | disclosed |
| CN-107949635-A | For characterizing time-based hepatotoxic method | 休雷尔公司 | 2018-04-20 | — | — | CN | disclosed |