Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15707369 | 0.80 | KDM4C (0.56) | KDM4CMAPTKDM4EALDH1A1GAA | |
| SCHEMBL18971775 | 0.80 | KDM4C (0.56) | KDM4CKDM4EALDH1A1GAALMNA | |
| Hydrochloric Acid SCHEMBL18940405 | 0.78 | KDM4C (0.55) | KDM4CKDM4EALDH1A1GAALMNA | |
| SCHEMBL30504022 | 0.78 | KDM4C (0.67) | KDM4CKDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL21314979 | 0.78 | KDM4C (0.67) | KDM4CKDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL18940385 | 0.77 | KDM4C (0.54) | KDM4CKDM4EALDH1A1GAALMNA | |
| SCHEMBL20083647 | 0.76 | KDM4C (0.53) | KDM4CMAPTKDM4EALDH1A1GAA | |
| SCHEMBL18612868 | 0.72 | KDM4C (0.69) | KDM4CKDM4EALDH1A1GAALMNA | |
| SCHEMBL16032991 | 0.72 | KDM4C (1.00) | KDM4C | |
| SCHEMBL18940383 | 0.72 | KDM4C (0.53) | KDM4CCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922386-A | 1,4 disubstituted imidazolium derivatives | 大日本住友制药株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107922348-A | Bicyclic heterocyclic amide derivatives | 大日本住友制药株式会社 | 2018-04-17 | — | — | CN | disclosed |