Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800456 | 0.88 | KMT2A (0.44) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL28239200 | 0.78 | APP (0.40) | KMT2AALDH1A1KDM4ELMNAKEAP1 | |
| SCHEMBL28226853 | 0.71 | KMT2A (0.41) | KMT2AALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL28728906 | 0.70 | — | — | |
| SCHEMBL1662536 | 0.70 | MAPT (0.43) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL5075060 | 0.67 | MEN1 (0.44) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL3976134 | 0.66 | F2 (0.44) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL29082277 | 0.66 | MAPT (0.51) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL2678329 | 0.65 | CA1 (0.50) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL14736112 | 0.65 | MAPT (0.54) | KMT2AALDH1A1MEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143708-A | Polysubstituted benzazepine heteroaryl derivative and application thereof | 四川汇宇制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115536776-A | Resin for photoresist, preparation method thereof and photoresist prepared from resin | 瑞红(苏州)电子化学品股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-108290903-B | Novel macrocyclic sulfondiimine compounds | 拜耳医药股份有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-108530315-A | O- substituted hydroxylamine hydrochlorides and preparation method thereof | 苏州昊帆生物股份有限公司 | 2018-09-14 | — | — | CN | disclosed |
| CN-107954999-A | Han oxadiazole rings compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2018-04-24 | — | — | CN | disclosed |