Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785830 | 0.84 | POLB (0.47) | APPKMT2APOLBALDH1A1HCRTR2 | |
| SCHEMBL28210344 | 0.78 | KMT2A (0.42) | KMT2AALDH1A1KDM4ELMNAKEAP1 | |
| SCHEMBL3300843 | 0.75 | GAA (0.45) | POLBALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3517002 | 0.74 | CNR2 (0.44) | APPPOLBALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4538192 | 0.73 | ALDH1A1 (0.49) | KMT2APOLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11790689 | 0.72 | MCHR1 (0.52) | POLBALDH1A1GAALMNA | |
| SCHEMBL11785484 | 0.69 | PPARG (0.43) | KMT2APOLBALDH1A1PPARGGAA | |
| SCHEMBL1157467 | 0.69 | GAA (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL20983506 | 0.69 | MCHR1 (0.39) | APPKMT2AALDH1A1HCRTR2CYP3A4 | |
| SCHEMBL1771384 | 0.69 | STAT3 (0.42) | KMT2APOLBALDH1A1PPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530315-A | O- substituted hydroxylamine hydrochlorides and preparation method thereof | 苏州昊帆生物股份有限公司 | 2018-09-14 | — | — | CN | disclosed |