Aniline

Aniline

SCHEMBL28210652

CC1(C)CCC(C)(C)N1[O].Nc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
BACE1 P56817 5/20 0.37
HSD11B1 P28845 2/20 0.37
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP3A4 P08684 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GRM5 P41594 2/20 0.34
OPRM1 P35372 2/20 0.33
REN P00797 1/20 0.33
APP P05067 1/20 0.33
BACE2 Q9Y5Z0 1/20 0.33
DHFR P00374 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440388 0.73 ALDH1A1 (0.40) TSHRBACE1HSD11B1MEN1KMT2A
Hydroxyamine SCHEMBL12488720 0.71 FFAR3 (0.30)
Benzoic Acid SCHEMBL17838773 0.69 TSHR (0.50) TSHRMEN1MAPTKMT2ACYP3A4
Methyl Alcohol SCHEMBL4958474 0.69 FFAR3 (0.32) TSHR
Aniline SCHEMBL8757361 0.69 TSHR (0.73) TSHRMEN1MAPTPKMHTT
Aniline SCHEMBL11818606 0.68
Aniline SCHEMBL27831713 0.68
Aniline SCHEMBL9864514 0.68 TSHR (0.85) TSHRMEN1MAPTPKMHTT
Aniline SCHEMBL1984004 0.68
SCHEMBL18517570 0.68 TSHR (1.00) TSHRMEN1MAPTPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105826563-B A kind of free radical polyalcohol material and its preparation and application 武汉理工大学 2018-05-01 CN disclosed