Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28774150 | 0.86 | ALDH1A1 (0.40) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL6678293 | 0.81 | PRKCI (0.41) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL28097911 | 0.81 | PRKCI (0.37) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL2339661 | 0.79 | MAPT (0.41) | PRKCIACHECASP1MAPTTDP1 | |
| SCHEMBL30227313 | 0.79 | MAPT (0.41) | PRKCIACHECASP1MAPTTDP1 | |
| SCHEMBL28248000 | 0.79 | CSNK1E (0.38) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL21753786 | 0.77 | PRKCI (0.34) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL30227490 | 0.76 | ALDH1A1 (0.50) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL94119 | 0.76 | ALDH1A1 (0.50) | PRKCIACHECASP1MAPTPOLB | |
| SCHEMBL3839781 | 0.76 | PRKCI (0.39) | PRKCIACHECASP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103735554-B | Inhibitors of protein aggregation | 维斯塔实验室有限公司 | 2018-03-20 | — | — | CN | disclosed |