Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924727 | 0.83 | GPR84 (0.58) | GPR84ATMHTR2AFFAR1HTR2C | |
| SCHEMBL1224614 | 0.80 | GPR84 (0.64) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL30552280 | 0.80 | GPR84 (0.64) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL18708141 | 0.77 | GPR84 (0.50) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL12120939 | 0.75 | GPR84 (0.58) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL13969931 | 0.75 | GPR84 (0.48) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL3614670 | 0.75 | CYP2A6 (0.55) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL12093634 | 0.75 | GPR84 (0.58) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL31663257 | 0.75 | CYP2A6 (0.55) | GPR84ATMHTR2AKDM4EMEN1 | |
| SCHEMBL398138 | 0.75 | GPR84 (0.48) | GPR84ATMHTR2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137542-A | Pyridone diformamide as bromine structural domain inhibitor | 葛兰素史克知识产权第二有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107873030-A | 5‑HT2CReceptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2018-04-03 | — | — | CN | disclosed |