SCHEMBL28210883

SCHEMBL28210883

CCSCCCOCCCSCC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP3A4 P08684 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25996468 0.92 TSHR (0.41) TSHRMEN1KMT2ATDP1CYP3A4
SCHEMBL25996469 0.89 MEN1 (0.39) TSHRMEN1KMT2ATDP1CYP3A4
SCHEMBL14996462 0.89
SCHEMBL14493348 0.88 HTT (0.50) TSHRMEN1KMT2ATDP1ALDH1A1
SCHEMBL5596561 0.88 TSHR (0.35) TSHRMEN1KMT2ATDP1
SCHEMBL17225877 0.88 TSHR (0.35) TSHRMEN1KMT2ATDP1CYP3A4
SCHEMBL5596635 0.85
SCHEMBL18511820 0.83 THRB (0.45) TSHRMEN1KMT2ATDP1CYP3A4
SCHEMBL18511781 0.83 THRB (0.45) TSHRMEN1KMT2ATDP1CYP3A4
SCHEMBL22268947 0.83 THRB (0.45) TSHRMEN1KMT2ATDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107827792-B A kind of method and method of purification synthesizing 1,5,13- trihydroxy -7- oxa- -3,11- dithia tridecane 锦西化工研究院有限公司 2019-07-19 CN disclosed
CN-107827792-A Synthesize the method and method of purification of the dithia tridecane of 1,5,13 trihydroxy of high-purity, 7 oxa- 3,11 锦西化工研究院有限公司 2018-03-23 CN disclosed