Acetic Acid Methyl Ester

Acetic Acid Methyl Ester

SCHEMBL28210952

COC(C)=O.COc1cscc1OC

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TNFSF11 O14788 1/20 0.41
LMNA P02545 1/20 0.39
CYP3A4 P08684 5/20 0.38
HTT P42858 1/20 0.38
TSHR P16473 2/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
CA3 P07451 1/20 0.34
PKM P14618 1/20 0.34
CA4 P22748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL6617803 0.85 CA12 (0.43) ALDH1A1LMNACYP3A4HTTTSHR
Ammonia Solution, Strong SCHEMBL28304171 0.79 CA1 (0.40) ALDH1A1LMNACYP3A4HTTTSHR
Water SCHEMBL27790537 0.79 CA1 (0.40) ALDH1A1LMNACYP3A4HTTTSHR
SCHEMBL1286669 0.77 HTT (0.48) ALDH1A1LMNACYP3A4HTTCA9
Ethylene SCHEMBL29270239 0.76 CA1 (0.38) ALDH1A1CYP3A4HTTTSHRCA12
SCHEMBL21617945 0.75 KDM4E (0.43) ALDH1A1TNFSF11LMNAHTTTSHR
1,2-Dimethoxybenzene SCHEMBL28254681 0.73 CA1 (0.65) ALDH1A1LMNAHTTTSHRCA12
Acetic Acid Methyl Ester SCHEMBL28750848 0.72
SCHEMBL10472449 0.71 KDM4E (0.43) ALDH1A1TNFSF11LMNATSHRKDM4E
SCHEMBL3063642 0.71 ALDH1A1 (0.35) ALDH1A1CYP3A4HTTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107880014-A Synthetic method of 3, 4-dimethoxythiophene 南京工业大学 2018-04-06 CN claimed