Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28210412 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27976306 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3865125 | 0.81 | KDM4E (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29457349 | 0.81 | KDM4E (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL31302096 | 0.80 | KDM4E (0.50) | ALDH1A1MAPTKDM4EL3MBTL1ATM | |
| SCHEMBL16890288 | 0.79 | KDM4E (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30717256 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1ATMHTR6 | |
| SCHEMBL25844972 | 0.79 | KDM4E (0.39) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27096205 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1ATMHTR6 | |
| SCHEMBL782631 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1ATMGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107868089-A | A kind of synthetic method of the Phenylindole of 5,12 dihydro 5 simultaneously [3,2 a] carbazole | 河南省科学院化学研究所有限公司 | 2018-04-03 | — | — | CN | claimed |
| CN-107868089-B | A kind of synthetic method of 5,12- dihydro -5- Phenylindole simultaneously [3,2-a] carbazole | 河南省科学院化学研究所有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-107868089-A | A kind of synthetic method of the Phenylindole of 5,12 dihydro 5 simultaneously [3,2 a] carbazole | 河南省科学院化学研究所有限公司 | 2018-04-03 | — | — | CN | disclosed |