Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844399 | 0.90 | CYP11B1 (0.54) | HDAC1HDAC2CYP11B1CYP11B2CCNE1 | |
| SCHEMBL2821094 | 0.84 | CYP2D6 (0.49) | HDAC1HDAC2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL8570310 | 0.83 | HDAC1 (0.56) | HDAC1HDAC2CYP11B1CYP11B2CCNE1 | |
| SCHEMBL2226543 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2CYP11B1CYP11B2QPCT | |
| SCHEMBL153089 | 0.82 | CYP11B1 (0.56) | HDAC1HDAC2CYP11B1CYP11B2CCNE1 | |
| SCHEMBL8911377 | 0.82 | HDAC1 (0.55) | HDAC1HDAC2CYP11B1CYP11B2QPCT | |
| SCHEMBL8971551 | 0.82 | HDAC1 (0.55) | HDAC1HDAC2CYP11B1CYP11B2CCNE1 | |
| SCHEMBL7104503 | 0.81 | CYP11B1 (0.51) | HDAC1HDAC2CYP11B1CYP11B2QPCT | |
| SCHEMBL27992982 | 0.79 | CYP11B1 (0.50) | HDAC1HDAC2CYP11B1CYP11B2QPCT | |
| SCHEMBL2226354 | 0.79 | CYP11B1 (0.53) | HDAC1HDAC2CYP11B1CYP11B2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | HDAC1 883/4885HDAC2 625/4885CYP11B1 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.