Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396105 | 0.91 | HPGDS (0.48) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL27369174 | 0.87 | HPGDS (0.47) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL152405 | 0.84 | HPGDS (0.50) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL2821115 | 0.84 | HDAC1 (0.56) | HPGDSHDAC1HDAC2SMN1; SMN2NPC1 | |
| SCHEMBL8655761 | 0.84 | HPGDS (0.45) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL8093091 | 0.84 | HRH1 (0.49) | CYP2D6CYP2C19CYP2C9CYP3A4HPGDS | |
| SCHEMBL23146081 | 0.78 | CYP2A6 (0.61) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL8655571 | 0.76 | CYP2C9 (0.46) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL2227620 | 0.76 | CYP3A4 (0.46) | CYP2D6CYP2C19CYP2C9CYP3A4CYP19A1 | |
| SCHEMBL12844399 | 0.74 | CYP11B1 (0.54) | HPGDSHDAC1HDAC2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARMACEUTICAL IND. CO., LTD. | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240890-A1 | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | CMA1, IL5, HRH4 | CYP2D6 546/4885CYP2C19 143/4885CYP2C9 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.