Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498175 | 0.88 | — | — | |
| SCHEMBL21178116 | 0.82 | DRD4 (0.40) | DRD4EPHX2AOC3ALDH1A1MEN1 | |
| SCHEMBL21178115 | 0.82 | DRD4 (0.40) | DRD4EPHX2AOC3ALDH1A1MEN1 | |
| SCHEMBL21178152 | 0.82 | DRD4 (0.40) | DRD4EPHX2AOC3ALDH1A1MEN1 | |
| SCHEMBL2586558 | 0.80 | KDM4C (0.43) | DRD4EPHX2AOC3ALDH1A1MEN1 | |
| SCHEMBL2586566 | 0.80 | KDM4C (0.43) | DRD4EPHX2AOC3ALDH1A1MEN1 | |
| SCHEMBL577126 | 0.79 | — | — | |
| SCHEMBL497630 | 0.79 | TSHR (0.38) | DRD4EPHX2AOC3ALDH1A1MEN1 | |
| SCHEMBL4299935 | 0.79 | DRD4 (0.41) | DRD4AOC3ALDH1A1KDM4EPOLB | |
| SCHEMBL9830249 | 0.78 | DRD4 (0.37) | DRD4AOC3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835812-A | Target mutant K RAS composition and method | 南特生物科学股份有限公司 | 2018-03-23 | — | — | CN | disclosed |